Go Back
Simon Nadal
CY Cergy Paris University
Contact
About
First Name
Simon
Last Name
Nadal
University
CY Cergy Paris University
Current position
Group Leader
Email
simon.nadal@cyu.fr
Personal webpage
www.nadal-lab.eu
Researcher Identification
ORCID
ORCID
0000-0002-0748-0284
Keywords
Multiple Myeloma ; Chemical Proteomics ; Minimal Residual Disease (MRD) monitoring by Mass Spectrometry ; Chemical Biology ; Epigenetics
Health related-scientific domains
Applied Medical Technologies, Diagnostics, Therapies
Life Sciences related to Health
Research expertise/competencies
Multiple Myeloma, Proteomics, Mass Spectrometry, Chemical Biology, Protein Chemistry, Synthetic proteins, Post-translational mutagenesis, Histone Post-translational modifications
Faculty / Institute / Department
Faculty of Sciences & Technology / Department of Chemistry
Research center/group
BioCIS : Biomolecules : Design, Isolation, Synthesis
Research center/group website
Available major infrastructure
- Fully equipped organic synthesis lab
- Fully equipped peptide synthesis platform (PeptLab)
- Fully equipped BSL-1 protein chemistry lab (recombinant protein production and purification, post-translational mutagenesis)
- BSL-2 Cell culture lab (human myeloma cell lines)
- Mass spectrometry: UPLC-Q-ToF (Waters), partnership access to nUPLC-ESI-Orbitrap (Thermo Orbitrap Eclipse)
Infrastructure website
Collaboration-based research services
- (Semi-) Synthesis of proteins carrying chemically-defined post-translational modifications (example histone mono/di/tri-methylation, phosphorylation, acetylation, GlcNAc glycosylation etc.) through post-translation chemical mutagenesis
Contractual research services
- The unit offers Peptide synthesis services via the PeptLab platform
Website describing services
Topics for collaboration
- Minimal residual disease monitoring in multiple myeloma
- Antigenic stimulation as growth stimulus in multiple myeloma
- Epigenetic changes in multiple myeloma
- Histone post-translational modifications in multiple myeloma
